Genes That up Bone Disease Risk Identified
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01 June 2011
Washington, DC USA
Scientists have identified genes which they claim could increase the risk of developing Paget’s disease — a chronic and painful bone condition that causes inflammation and deformity.
An international team, which has provided new insights into the genetics of bone disease, says that the findings may allow future genetic profiling to identify people at risk of the metabolic bone disease, the Nature Genetics reported.
According to the scientists, a large part of the genetic risk of Paget’s disease in individuals is accounted for by these genes, some of which are known to play important roles in bone metabolism, while others have not previously been linked to bone regulation.