Causes of Psoriasis
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In Psoriasis regeneration of cells of epidermal layer is abnormally accelerated. It takes only 5–6 days instead of 28days for the keratinocytes to travel the distance from lowermost layer to become the uppermost layer. In the bargain these cells do not mature in such a short time and remain immature hard and scaly. Before the superficial layer is shed off & cleared new layer of immature & ill–formed cells is laid, this results in piling up of scales and thickening of skin.
Moreover in order to maintain such an increased production of cells, demand for blood & other constituents for cell manufacture at that site is markedly increased. The blood circulation to that area is increased manifold leading to congestion, redness(Inflamation)of skin. Thus a psoritic patch is formed.
Contributed by Dr. R. S. Sonawane