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Clinical Features of Rubella

A large percentage of infections (50 to 65%) are asymptomatic. In a typical case, the clinical features comprise the following: Diagnosis of Rubella
Due to the mildness and variability of its symptoms, the disease could remain unrecognized unless it is an epidemic. A definitive diagnosis of rubella is possible only through virus isolation and serology. Throat swabs should be cultured for virus isolation, it takes longer than serological diagnosis. The most widely used serological test is the Hemagglutination Inhibition Test (HIT) developed in 1966.
Two blood samples are taken, the first sample within five days after the onset of illness, and the second, two weeks later. A fourfold rise in HL antibody titer in paired sera and presence of igM in a single serum sample obtained two weeks after the rash is diagnostic of recent rubella infection. More sensitive serological tests includes the ELISHA test and radio–immune assay.

Prevention of Rubella
Rubella Vaccine: This vaccine is administered in a single dose of 0.5 ml subcutaneously. After vaccination, the person may present with symptoms like fever, malaise, mild rash and arthralgia (pain in the joints). Infants under one year of age should not be vaccinated. The rubella vaccine is contraindicated in pregnancy. The vaccine also comes in a combined form of measles, mumps and rubella vaccine.