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A liver biopsy is a procedure by which a thin core of liver tissue is obtained for analysis under a microscope.

Complications of Liver Biopsy
Hemorrhage from Needle Biopsy
Bleeding in the liver from a needle biopsy, may, instead of reaching the peritoneal cavity, enter the biliary tract and escape into the gastrointestinal tract. This is known as hemobilia. It is a rare cause of G. I. bleeding. Early treatment is important since it has a significant mortality if not recognized and corrected.

Ordinarily a sharp drop in B.P. after a needle biopsy of the liver would suggest blood loss. There is often a slow pulse and sharp abdominal pain. It usually lasts an hour or so with recovery.

Bile Peritonitis
Instead of blood, there may be bile leakage from the liver after a needle liver biopsy. Bile escaping into the peritoneal cavity may produce bile peritonitis, with severe abdominal pain, fever and a “Shock–like” state; a situation requiring prompt therapy.

This is an uncommon but serious complication. It is usually controlled by observation and blood transfusion, but may require surgery to stop it.