K E M Hospital Research Center
Date and Year of Commencement: May 1997
Routine use of uterotonic agents after delivery reduces the incidence of post partum hemorrhage but these uterotonic agents have several drawbacks like administrative method is invasive and is associated with unpleasant side effects.
Misoprostol is effective, nonmotensive, orally administered, easily stored and associated with few side effects. The prostaglandin E1 analogue was compared prospectively with Oxytocin in the active management of third stage of labor.
To compare the efficacy of oral prostaglandin with Oxytocin in prevention of Atonic PPH at KEM Hospital, Pune.
It is a prospective study in which the two drugs namely Two Tablets of Cytotec 400 mcg and Inj. Oxytocin 10 units IM will be given in third stage of labor in an alternative manner.
Patients with bronchial asthma, major cardiovascular disorders and epilepsy were excluded from the study.
600 clients will be interviewed for this study in three distinct groups:
- Women presenting for early abortion: Married women presenting for either medical or easily surgical abortion will be asked to participate in the study.
- Husbands of abortion clients: Husbands of consenting abortion clients will be interviewed to further explore the role husbands play in abortion.
- Married men Age 45 or less receiving care at the hospital for non abortion related spouses will also be interviewed.
The study started in March 1999, In all 75 clients have been interviewed and the study will continue till 600 clients are interviewed.