aarogya.com
  • Home
  • Complementary Medicine
    • Ayurveda
    • Homeopathy
    • Naturopathy
    • Acupressure
    • Acupuncture
    • Aromatherapy
    • Batch Flower Remedies
    • Home Remedies
    • Massage
    • Yoga
    • Meditation
    • Reiki
    • Bodywork
    • Medical Palmistry
  • Conditions & Diseases
    • Acute Diarrheal Disease
    • Appendicitis
    • Blindness
    • Brucellosis
    • Chicken Pox
    • Conjunctivitis
    • Dysentery
    • Hookworm
    • Japanese Encephalitis
    • Lymphatic Filariasis
    • Plague
    • Rubella
    • Typhoid Fever
    • Yellow Fever
    • Allergy
    • Arthritis
    • Blood Pressure
    • Computer Health Hazards
    • Chikungunya Fever
    • Dengue
    • Guinea Worm
    • Influenza
    • Leprosy
    • Malaria
    • Poliomyelitis
    • Tetanus
    • Whooping Cough
    • Viral Hepatitis
    • Amebiasis
    • Asthma
    • Bronchitis
    • Diagnostic Tests
    • Cholera
    • Diphtheria
    • Hepatitis
    • Irritable Bowel Syndrome
    • Leptospirosis
    • Measles
    • Rabies
    • Tuberculosis
    • Yaws
  • Family Health
    • Children's Health
    • Diet & Nutrition
    • First Aid
    • Fitness
    • Humor & Trivia
    • Men's Health
    • Preventive Health
    • Senior's Health
    • Senior Citizen Corner
    • Teen’s Health
    • Vets and Pets
    • Women’s Health
  • Health Resources
    • Blood Donation
    • Career Opportunities
    • Daily Health Tips
    • Health Programs
    • Featured Hospitals
    • Medical Education
    • Health Professional's Negligence
    • Medical Tourism
    • Video Eye
    • Rural Health
    • Patients' Rights Forum
  • Insurance
    • Euthanasia
    • Health Insurance
    • Health Insurance Policies
    • Insurance Companies
    • Medical Ethics
    • Medical Jurisprudence
    • Research
    • Telemedicine
    • Compare Health Insurance
  • Sex & Sexuality
    • What is Sex & Sexuality?
    • FAQs
    • Marriage & Pregnancy
    • Sex Education
  • Support Groups
    • Addiction
    • Aids
    • Cancer
    • Epilepsy
    • Swine Flu
    • Blood Search
    • Vivah
    • Health Directory
    • Alzheimer's Disease
    • Medical Support Groups
    • Cardiology
    • Depression
    • Depression Screening Test
    • Diabetes
    • Disability
    • Kidney
    • Obesity
    • Pregnancy
    • Schizophrenia
    • Vitiligo
Aarogya.com
Marathi | Gujarati | Register | Login
  • Home
  • Specialties
  • Neurology
  • Charcot-Marie-Tooth Disorder

Charcot-Marie-Tooth Disorder

  • Print
Details
Hits: 15046
Page 3 of 3

Types and Causes of Charcot–Marie–Tooth Disorder

The nervous system consists of motor neurons and sensory neurons. One set of nerves carries messages from the brain outward to the rest of the body and one brings messages from the extremities back to the brain. Messages that travel from the brain down the spinal cord, through the lower motor neurons (such as the sciatic nerve of the leg) to the muscles of the body are part of the motor neuron circuitry. Messages that travel upward from the sensory input to the spinal cord and finally the brain are sent by sensory neurons.

The peripheral nervous system is also comprised of motor and sensory nerve fibers, and since Charcot–Marie–Tooth Disorder affects the peripheral nerves, it results in both motor symptoms (weakness and muscle wasting) and sensory symptoms (numbness). The peripheral nerves are often described as being like electrical wires with an inner core (the axon), which is wrapped in insulation (a sheath called myelin). When the myelin is damaged (Type 1 CMT), the nerve impulses are conducted more slowly than normal. If the axon itself is damaged (Type 2), the speed of nerve conduction is almost normal, but the strength of the signal is reduced.

All forms of Charcot–Marie–Tooth Disorder are either demyelinating or axonal in nature. Since Charcot–Marie–Tooth Disorder is a multi–gene disorder, there are many different defective genes, which cause the disorder. Since 1991, more than 30 different genes causing CMT have been identified and the loci are known for at least another ten causes.

Treatment and Management of Charcot–Marie–Tooth Disorder

Treatment of Charcot–Marie–Tooth Disorder is done in conjunction with medical professionals of various specialties. After diagnosis by a neurologist, CMT patients are usually directed to either a podiatrist for care of their foot problems, an orthotist for the manufacture and fitting of braces, an orthopaedic surgeon for surgeries to straighten toes, lengthen heel cords or lower arches, or a physical therapist or occupational therapist to design exercise programs to strengthen muscles or learn energy conservation.

Although there is no cure for Charcot–Marie–Tooth Disorder at the present time, there are many therapies that can greatly improve life and function for CMT patients. The general advice for patients seeking assistance is to look first for the least invasive way to correct their problems.

In general, it is important for people with Charcot–Marie–Tooth Disorder to maintain what movement, muscle strength and flexibility they have. Hence, physical therapy and moderate activity are recommended. Overexertion, however, should be avoided. Swimming or water therapy is an excellent form of exercise since it does not put undue stress on the joints. A physical therapist can design an exercise program that fits a patient’s personal strengths and flexibility. It is impossible to build up muscles already atrophied by CMT, so the best program works on strengthening unaffected muscles that can help do the work of those that have atrophied because of CMT.

Bracing is another non–invasive form of correcting problems caused by CMT. Often gait abnormalities can be corrected by the use of either articulated (hinged) or unarticulated, molded braces called AFOs (ankle–foot orthoses). These braces help control foot drop and ankle instability and often provide a better sense of balance for patients. There are many new forms of bracing available for CMT patients, depending, of course, on the severity of their foot deformities and muscle weaknesses.

Appropriate footwear is important for people with CMT. Because of lack of good sensory reception in the feet, Charcot–Marie–Tooth Disorder patients may also need to see a podiatrist for help in trimming nails or removing calluses that develop on the pads of the feet. It is important to consult a medical professional so that the patient does not injure himself/herself doing these procedures.

The final decision a patient might make in caring for his/her foot or leg deformities is to have surgery. Many patients choose to stabilize their feet or correct progressive problems. These procedures include straightening and pinning the toes, lowering the arch, and sometimes, fusing the ankle joint to provide stability. Recovery from these surgeries can be long and sometimes difficult. Before considering surgery, a patient should always ask what the benefits may reasonably be considered to be and that must be weighed against the problems that might be incurred.

An additional problem related to Charcot–Marie–Tooth that needs to be addressed by a medical professional is the pain that some patients experience. Pain might be sharp and sudden or the gnawing, continuous ache of chronic pain. Some pain is associated with dysfunctional nerves that fire off sporadically and some can be attributed to weakened and poorly functioning muscles. Joints and ligaments in the feet and ankles are often painful because of the extra strain put on them by other muscles that have been rendered useless by CMT. Because the causes of pain vary, so will the treatments. No one, however, should be told that there is no pain associated with CMT, since pain is experienced in a very personal and individual way.

Although medical professionals are involved in many stages and forms of treatment, the patients themselves are responsible for much of the management of their CMT. Basically, people with Charcot–Marie–Tooth Disorder are healthy individuals and they must work to maintain that health. Because circulation is a problem in individuals with Charcot–Marie–Tooth, people must take care to keep their hands and feet as warm as possible. They also should take extra care to avoid falling because fractures take longer to heal in someone with an underlying disease process. Additionally, the resulting inactivity may cause the CMT to worsen. Falls can generally be avoided by watching where one walks and by wearing appropriate footwear.

There is no magic nutritional diet to treat Charcot–Marie–Tooth Disorder, but it is important for CMT patients to control their weight. Not only does extra weight make physical activity more difficult, but it also increases the stress on already compromised joints and muscles.

It is also important for patients to maintain as much strength and flexibility as possible. Generally, patients should consult a physical therapist or physician before beginning an exercise program, and avoid strenuous activity and overwork. Moderate activity and physical exercise can be beneficial, but patients must be conscious of their physical limitations. Patients must learn to say no to tasks that overwhelm them and to delegate tasks to other members of their family when possible.

Finally, stress management is important in maintaining a healthy body. Any disabling condition can affect the way people think and feel about themselves, but having a chronic illness like Charcot–Marie–Tooth Disorder, which is often unseen, places stress on individuals and often causes depression. People with Charcot–Marie–Tooth Disorder can suffer from low self–esteem and relationships with others can be affected. Even when a person has learned to live with Charcot–Marie–Tooth Disorder, the progressive nature of the disorder may bring about more loss and the grieving process can begin again.

Some patients cope successfully on their own or with the support of family and friends; others find it therapeutic to talk to a professional counselor or to participate in a support group

References

  • www.lindacrabtree.com
  • www.cmt.org.uk
  • www.hnf–cure.org
  • www.charcot–marie–tooth.org
  • 1
  • 2
  • 3

1

Neurology

  • FAQs on Brain Surgery
  • FAQs on Stroke
  • FAQs on Childhood Seizures
  • FAQs on Down Syndrome
  • FAQs on AntiDepressant
  • FAQs on Depression
  • FAQs on Parkinson's Disease
  • FAQs on Alzheimer's
  • Charcot-Marie-Tooth Disorder
  • Neuroscience on the Internet
  • Operation Theatre of the Future
  • Computers in Neurosurgery
  • Using Neuroscience for Brain Tumor
  • Neuroscience in Brain Transplantation
  • Brain Surgery
  • Neuroscience
  • Treatment of Phobias
  • What are Phobias?
  • Theories about Causes of Anxiety Disorders
  • Panic Disorders
  • Generalized Anxiety Disorder
  • What is Movement Disorder?
  • Learn about Cerebral Palsy
  • What is Stroke?
  • What are Pinched Nerves?
  • What is Meningitis?
  • What is Dementia?
  • What is Bell's Palsy?
  • Alzheimer's Disease
  • Acid Maltase Deficiency
  • Signs & Symptoms of Brain Tumor
  • Brain Tumors
  • Brain Cancer
  • About Brain
Introducing Digital Practice for Doctors & Healthcare professionals
Swine Flu
National Award for Outstanding achievement by a Non-Professional - Tushar Sampat
Health Professional's Negligence
Health Professional's Negligence
Records of published articles in the newspapers helps common people about precautions to be taken while seeking the services from health professionals and also helps health professionals to rectify the negligence.
read more…
Specialties
Common Symptoms


Aarogya Network

aarogya.com aims to be India’s leading comprehensive health information portal. The site has sections, which cover almost all the medical specialties and give useful information on various diseases. To enhance its reach, the content is available in Indian languages too. We were the first health website to introduce online support groups. Addiction support and Epilepsy support are examples of some very active and vibrant communities.

» Click here to see all our support groups

Subscribe to Our Newsletter

 Get health related new information.

Pune Aarogya
Digital Media Dedicated to Healthcare of Punekars

Health Tools

  • Health Directory
  • Message Board
  • Health Calculators
  • Depression Screening Test

About Aarogya.com

aarogya.com aims to be India’s leading comprehensive health information portal. The site has sections, which cover almost all the medical specialties

Read more...

Suggestions

This is YOUR site, so if you have suggestions or feedback on how we can improve it for you, please let us know! We do our best to keep up!

Read more...

User Comments

“My name is Paulette Conners and I just had to send you an email thanking you since one of the pages on your site was very helpful!”

  • About Us
  • Company Profile
  • Contact Us
  • Privacy Policy
  • Feedback
  • Disclaimer
  • Sitemap
  • Invite Your Friends

© 2017 www.aarogya.com. All Rights Reserved.